Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 12/20 | 0.46 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.45 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907725 | 1.00 | MAOB (0.48) | MAOBNR4A2GPR132CMKLR2CMKLR1 | |
| SCHEMBL7910954 | 0.89 | GPR132 (0.49) | MAOBGPR132 | |
| SCHEMBL7910951 | 0.89 | GPR132 (0.49) | MAOBGPR132 | |
| SCHEMBL7907454 | 0.89 | GPR132 (0.54) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL7907451 | 0.89 | GPR132 (0.54) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL7901041 | 0.88 | MAOB (0.54) | MAOBNR4A2 | |
| SCHEMBL7900921 | 0.88 | MAOB (0.54) | MAOBNR4A2 | |
| SCHEMBL7900916 | 0.88 | MAOB (0.54) | MAOBNR4A2 | |
| Water SCHEMBL7900960 | 0.88 | GPR132 (0.53) | GPR132CMKLR2CMKLR1 | |
| Water SCHEMBL7900958 | 0.88 | GPR132 (0.53) | GPR132CMKLR2CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |