SCHEMBL790785

SCHEMBL790785

c1ccc(C(c2ccccc2)(c2ccccc2)c2cccs2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RGS12 O14924 1/20 0.45
KIF11 P52732 1/20 0.41
TSHR P16473 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KCNN4 O15554 1/20 0.40
CHRM3 P20309 6/20 0.38
CHRM2 P08172 5/20 0.38
CHRM1 P11229 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 1/20 0.34
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGDS O60760 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682519 0.88 RGS12 (0.43) RGS12KIF11TSHRALDH1A1SMN1; SMN2
SCHEMBL1274370 0.84 SMN1; SMN2 (0.44) RGS12KIF11SMN1; SMN2MEN1GAA
SCHEMBL1274088 0.81 KCNN4 (0.50) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL11176882 0.79 KIF11 (0.41) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL14498132 0.79 KCNN4 (0.56) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL2390466 0.77 RGS12 (0.43) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL2390819 0.77 RGS12 (0.43) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL29064510 0.77 ESR1 (0.43) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL27564815 0.77 CNR1 (0.49) RGS12KIF11TSHRALDH1A1KCNN4
SCHEMBL11827348 0.77 TSHR (0.42) RGS12KIF11TSHRALDH1A1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007118474-A2 METHOD FOR THE PRODUCTION OF HYDROGEN-RICH SILANES, AND NOVEL CHEMICAL COMPOUNDS TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) 2007-10-25 WO claimed
EP-0818443-B1 Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases AMERICAN CYANAMID CO (US) 2001-12-05 EP claimed
US-6320040-B1 PREPARING NOVEL NUCLEOSIDE OLIGOMERS BEARING PENDANT CONJUGATE GROUPS FOR INCORPORATION INTO NUCLEIC ACIDS ISIS PHARMACEUTICALS, INC. 2001-11-20 US claimed
US-6124502-A Mercaptoketones and mercaptoalcohols and a process for their preparation AMERICAN CYANAMID COMPANY (US) 2000-09-26 US claimed
US-5852213-A Mercaptoketones and mercaptoalcohols and a process for their preparation AMERICAN CYANAMID COMPANY (US) 1998-12-22 US claimed
EP-0818443-A2 Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases American Cyanamid Company (US) 1998-01-14 EP claimed
US-5608046-A Conjugated 4'-desmethyl nucleoside analog compounds ISIS PHARMACEUTICALS, INC. (US) 1997-03-04 US claimed
US-4921978-A Process for the preparation of a macrolide compound AMERICAN CYANAMID COMPANY (US) 1990-05-01 US claimed
EP-0307226-A2 Process for the preparation of a macrolide compound AMERICAN CYANAMID COMPANY (US) 1989-03-15 EP claimed
CN-120166835-A Photoelectric device, preparation method of photoelectric device and electronic equipment 广东聚华新型显示研究院 2025-06-17 CN disclosed
CN-120166849-A Photoelectric device, preparation method of photoelectric device and electronic equipment TCL科技集团股份有限公司 2025-06-17 CN disclosed
CN-120166902-A Method for preparing metal oxide material, photoelectric device and electronic equipment comprising metal oxide material 广东聚华新型显示研究院 2025-06-17 CN disclosed
CN-120166852-A Photoelectric device and preparation method thereof TCL科技集团股份有限公司 2025-06-17 CN disclosed
CN-120166846-A Light emitting device, manufacturing method of light emitting device and electronic equipment TCL科技集团股份有限公司 2025-06-17 CN disclosed
US-4587241-A ANTIBIOTICS, BACTERICIDES SCHERING CORPORATION (US) 1986-05-06 US disclosed
EP-0178089-A1 2(N-heterocyclyl)penems SCHERING CORPORATION (US) 1986-04-16 EP disclosed
US-4540579-A 2-[(R) Amino acid alkyl]penems SCHERING CORPORATION (US) 1985-09-10 US disclosed
US-4540580-A 2-[(1'R)-1'-Aminoalkyl]penems SCHERING CORPORATION (US) 1985-09-10 US disclosed
US-4346187-A AND ORGANIC BROMINE COMPOUND BORG-WARNER CHEMICALS, INC. (US) 1982-08-24 US disclosed
US-4119638-A Thio-ester of 1 (p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid G. D. SEARLE & CO. (US) 1978-10-10 US disclosed