Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789883 | 0.85 | MAP4K4 (0.54) | HTTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23756982 | 0.79 | HTT (0.52) | ALOX15HTTMEN1KMT2ARAB9A | |
| SCHEMBL30514939 | 0.79 | HTT (0.52) | ALOX15HTTMEN1KMT2ARAB9A | |
| SCHEMBL31419248 | 0.78 | GRM1 (0.51) | ALOX15HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL23757853 | 0.78 | HTT (0.51) | ALOX15HTTMEN1KMT2ARAB9A | |
| SCHEMBL23774957 | 0.78 | HTT (0.51) | ALOX15HTTKMT2ARAB9ANPC1 | |
| SCHEMBL23756763 | 0.78 | HTT (0.51) | ALOX15HTTMEN1KMT2ARAB9A | |
| SCHEMBL29875621 | 0.78 | HTT (0.51) | ALOX15HTTMEN1KMT2ARAB9A | |
| SCHEMBL29437732 | 0.77 | ALOX15 (0.57) | ALOX15HTTEGFRMEN1KMT2A | |
| SCHEMBL26613609 | 0.77 | ALOX15 (0.57) | ALOX15HTTEGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |