Methacrylic Acid

Methacrylic Acid

SCHEMBL7908009

C=C(C)C(=O)O.C=C(C)C(=O)OCCCC.C=CC(=O)OCCCC

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.69
HPGD P15428 1/20 0.69
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 1/20 0.50
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 3/20 0.47
THRB P10828 4/20 0.45
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10477469 0.96 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4ATM
Methacrylic Acid SCHEMBL7730831 0.96 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL313059 0.95 TSHR (0.76) TSHRHPGDALDH1A1CYP3A4ATM
Methacrylic Acid SCHEMBL10482185 0.94 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL7567268 0.94 TSHR (0.73) TSHRHPGDALDH1A1CYP3A4ATM
Methacrylic Acid SCHEMBL168599 0.94 TSHR (0.79) TSHRHPGDALDH1A1CYP3A4ATM
Methacrylic Acid SCHEMBL2152133 0.94 TSHR (0.79) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid Ethyl Ester SCHEMBL17956897 0.93 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL27902957 0.92 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1514903 0.92 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015157552-A1 CATALYST RESIN ROHM AND HAAS COMPANY (US) 2015-10-15 WO disclosed
WO-2015157551-A1 CATALYST RESIN ROHM AND HAAS COMPANY (US) 2015-10-15 WO disclosed
US-6200672-B1 METAL SHEET IS COATED WITH A COMPLEX AND/OR SALT OF A RARE EARTH METAL AND ORGANIC COMPOUND, E.G CATECHOL, PYRIDINE-CARBOXYLIC ACID, AND A MATRIX WHICH PHYSICALLY HOLDS THE ABOVE AND HAS ADHESION FOR METAL; CORROSION RESISTANCE NIPPON STEEL CORPORATION (JP) 2001-03-13 US disclosed
US-5897948-A NONLEACHED PROTECTIVE COATINGS COMPRISING A MATRIX RESIN WITH DISPERSED CHROMATE COLLOID PARTICLES; CORROSION RESISTANCE, STABILITY NIPPON STEEL CORPORATION (JP) 1999-04-27 US disclosed
EP-0776992-A1 SURFACE-TREATED STEEL SHEET HAVING CHEMICAL CONVERSION RESIN COATING AND PROCESS FOR PRODUCING THE SAME Nippon Steel Corporation (JP) 1997-06-04 EP disclosed