Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717068 | 1.00 | LMNA (0.49) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL3294831 | 1.00 | LMNA (0.49) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL9750464 | 0.98 | LMNA (0.46) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL11717064 | 0.93 | LMNA (0.45) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL7908327 | 0.93 | LMNA (0.45) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL9175094 | 0.89 | LMNA (0.42) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL11203213 | 0.86 | KDM4C (0.35) | LMNAMAPT | |
| SCHEMBL10507835 | 0.86 | LMNA (0.46) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL8827957 | 0.84 | LMNA (0.36) | LMNAMAPTDGKAMAPK1 | |
| SCHEMBL3583182 | 0.84 | LMNA (0.36) | LMNAMAPTDGKAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197895-B1 | ADDING A CERTAIN AMOUNT OF AN ORGANIC PEROXIDE INTO THE REACTION VESSEL TO SHORTEN THE TIME FOR CHLORINATION REACTION WITHOUT SACRIFICING THE INITIAL COLORING AND THE HEAT STABILITY | KANEKA CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |