Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.57 |
| ▸ | AGT | P01019 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860958 | 0.95 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL7303260 | 0.93 | AGTR1 (0.61) | AGTR1AGTR2AGT | |
| SCHEMBL7297174 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL14855464 | 0.90 | AGTR1 (0.62) | AGTR1AGTR2AGT | |
| SCHEMBL7306979 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL9276766 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL7311109 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2AGT | |
| SCHEMBL14855371 | 0.88 | AGT (0.60) | AGTR1AGTR2AGT | |
| SCHEMBL12991387 | 0.88 | AGT (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL7301221 | 0.88 | AGTR1 (0.64) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |