Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903966 | 0.72 | NPC1 (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL7896414 | 0.70 | HRH3 (0.39) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL7905792 | 0.70 | NPC1 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL7904727 | 0.69 | GAA (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL7896426 | 0.69 | MAPK1 (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7905953 | 0.66 | RAB9A (0.45) | KDM4EALDH1A1NPC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL7908541 | 0.66 | RAB9A (0.44) | KDM4EALDH1A1NPC1LMNARAB9A | |
| SCHEMBL9735041 | 0.63 | TSHR (0.38) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3559160 | 0.62 | MAPT (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3209012 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |