Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686142 | 0.79 | MAPK1 (0.36) | MAPK1SMN1; SMN2HTR2ALMNAPDK2 | |
| SCHEMBL15642615 | 0.79 | MAPK1 (0.36) | MAPK1SMN1; SMN2HTR2ALMNAPDK2 | |
| SCHEMBL27556275 | 0.78 | PDK2 (0.50) | PDK2 | |
| SCHEMBL18171078 | 0.75 | HSP90AA1 (0.34) | MAPK1SMN1; SMN2HTR2ALMNA | |
| SCHEMBL21801589 | 0.75 | MAPK1 (0.34) | MAPK1SMN1; SMN2HTR2ALMNAPDK2 | |
| SCHEMBL30657026 | 0.75 | KDM1A (0.48) | MAPK1SMN1; SMN2HTR2ALMNA | |
| SCHEMBL1535911 | 0.75 | KDM1A (0.48) | MAPK1SMN1; SMN2HTR2ALMNA | |
| SCHEMBL15868570 | 0.75 | HTR2A (0.42) | MAPK1SMN1; SMN2HTR2ALMNA | |
| Ammonia Solution, Strong SCHEMBL7599790 | 0.73 | HTR2A (0.41) | MAPK1SMN1; SMN2HTR2ALMNA | |
| Benzene SCHEMBL11415270 | 0.73 | KDM1A (0.47) | MAPK1SMN1; SMN2HTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197994-B1 | PREPARING VICINAL DIOLS BY CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS USING SILICA GEL SUPPORTED BIS-CINCHONA ALKALOID DERIVATIVE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-03-06 | — | — | US | disclosed |
| US-5968867-A | REUSABLE CATALYSTS FOR DIHYDROXYLATION OF OLEFINS TO OPTICALLY-ACTIVE VICINAL DIOLS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1999-10-19 | — | — | US | disclosed |