Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899656 | 1.00 | HIF1A (0.48) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL7899659 | 1.00 | HIF1A (0.48) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL4559206 | 0.90 | ABCC4 (0.44) | HIF1ASMN1; SMN2TAAR1CYP1A2CYP2C9 | |
| SCHEMBL7908936 | 0.85 | SMN1; SMN2 (0.52) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL7908766 | 0.85 | SMN1; SMN2 (0.52) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL687447 | 0.85 | SMN1; SMN2 (0.52) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL8578371 | 0.83 | SMN1; SMN2 (0.50) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL8578380 | 0.83 | SMN1; SMN2 (0.50) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL29985359 | 0.83 | GAA (0.46) | HIF1ASMN1; SMN2SLC6A2TAAR1FDPS | |
| SCHEMBL12315581 | 0.80 | GAA (0.50) | HIF1ASMN1; SMN2KMT2AARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |