SCHEMBL29985359

SCHEMBL29985359

CCCCC(O)(Cc1ccccc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
SCN5A Q14524 3/20 0.42
SCN9A Q15858 3/20 0.42
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
MMP13 P45452 1/20 0.40
KIF11 P52732 1/20 0.40
ARG1 P05089 1/20 0.39
ARG2 P78540 1/20 0.39
SLC6A2 P23975 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
EPHX2 P34913 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12315581 0.94 GAA (0.50) GAAKMT2ASMN1; SMN2HIF1ASCN5A
SCHEMBL7023498 0.87 KMT2A (0.52) GAAKMT2ATDP1L3MBTL1SMN1; SMN2
SCHEMBL7899656 0.83 HIF1A (0.48) KMT2ASMN1; SMN2HIF1AALDH1A1MAPT
SCHEMBL7899659 0.83 HIF1A (0.48) KMT2ASMN1; SMN2HIF1AALDH1A1MAPT
SCHEMBL7908776 0.83 HIF1A (0.48) KMT2ASMN1; SMN2HIF1AALDH1A1MAPT
SCHEMBL29450628 0.82 SMN1; SMN2 (0.44) SMN1; SMN2HIF1ASCN5ASCN9AMMP1
SCHEMBL28095334 0.81 ARG1 (0.52) SMN1; SMN2HIF1AMMP1MMP9MMP13
SCHEMBL20816220 0.81 GAA (0.52) GAAKMT2ASCN5ASCN9AMMP1
SCHEMBL3736928 0.81 GAA (0.52) GAAKMT2ATDP1L3MBTL1SMN1; SMN2
SCHEMBL4380578 0.80 SMN1; SMN2 (0.46) SMN1; SMN2HIF1AALDH1A1ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12139608-B2 Non-halogenated flame retardant polyamide compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2024-11-12 US disclosed
US-20240191075-A1 FLAME RETARDANT POLYAMIDE COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2024-06-13 US disclosed
US-11826984-B2 Polyamide-metal laminates DUPONT POLYMERS, INC. (US) 2023-11-28 US disclosed
US-20230001669-A1 POLYAMIDE-METAL LAMINATES CELANESE POLYMERS HOLDING, INC. 2023-01-05 US disclosed
EP-4065361-A1 POLYAMIDE-METAL LAMINATES DUPONT POLYMERS, INC. (US) 2022-10-05 EP disclosed