Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.69 |
| ▸ | HTR1D | P28221 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192822 | 0.92 | MTNR1A (0.62) | HTR1BHTR1DKDM4ELMNATDP1 | |
| Hydrochloric Acid SCHEMBL9133314 | 0.90 | MTNR1A (0.60) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL6318521 | 0.87 | HTR1B (0.73) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL32679977 | 0.86 | GAA (0.64) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL18551224 | 0.86 | HRH1 (0.62) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL7060492 | 0.86 | HRH1 (0.62) | HTR1BHTR1DLMNATDP1HRH1 | |
| SCHEMBL8596340 | 0.86 | HTR1B (0.59) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL6949179 | 0.86 | MEN1 (0.62) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL13715506 | 0.86 | GAA (0.64) | HTR1BHTR1DKDM4ELMNATDP1 | |
| SCHEMBL5362726 | 0.86 | HTR1B (0.59) | HTR1BHTR1DKDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |