Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789600 | 0.98 | HRH3 (0.55) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL789819 | 0.85 | HRH3 (0.53) | HRH3ALDH1A1SMN1; SMN2HTTNCF1 | |
| SCHEMBL15132866 | 0.82 | HRH3 (0.59) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL19211682 | 0.81 | ALDH1A1 (0.65) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL3381044 | 0.81 | ESR1 (0.55) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL23430815 | 0.80 | HRH3 (0.63) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL4146260 | 0.79 | HRH3 (0.57) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL31082092 | 0.78 | ALDH1A1 (0.60) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL623389 | 0.78 | SMN1; SMN2 (0.65) | HRH3ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL16945880 | 0.77 | ALDH1A1 (0.55) | HRH3ALDH1A1SMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |