Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857778 | 1.00 | MAPT (0.32) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2299371 | 1.00 | MAPT (0.32) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31547150 | 0.98 | ALDH1A1 (0.32) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11858505 | 0.98 | ALDH1A1 (0.32) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL24603326 | 0.91 | ALDH1A1 (0.30) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3859583 | 0.91 | ALDH1A1 (0.30) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3859581 | 0.91 | ALDH1A1 (0.30) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28878206 | 0.89 | MAPT (0.31) | MAPT | |
| SCHEMBL11869711 | 0.89 | MAPT (0.31) | MAPT | |
| SCHEMBL30053313 | 0.89 | MAPT (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |