Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677624 | 0.97 | RARB (0.68) | RARBTSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL18314362 | 0.95 | RARB (0.71) | RARBTSHRTP53PLA2G4B | |
| SCHEMBL677599 | 0.95 | RARB (0.71) | RARBTSHRTP53PLA2G4B | |
| SCHEMBL9378715 | 0.95 | TSHR (0.60) | RARBTSHRTP53PLA2G4BSLC2A1 | |
| SCHEMBL19130182 | 0.92 | TP53 (0.66) | RARBTSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL19130711 | 0.90 | TP53 (0.69) | RARBTSHRTP53PLA2G4B | |
| SCHEMBL13385664 | 0.90 | TP53 (0.69) | RARBTSHRTP53PLA2G4B | |
| SCHEMBL19130183 | 0.90 | TP53 (0.69) | RARBTSHRTP53PLA2G4B | |
| SCHEMBL11680771 | 0.88 | L3MBTL1 (0.60) | TSHRTP53PLA2G4BSLC2A1L3MBTL1 | |
| SCHEMBL99263 | 0.85 | GAA (0.57) | RARBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075215-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |