Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5524477 | 0.98 | HTR2A (0.61) | HTR2ATAAR1NR5A1SMN1; SMN2GLA | |
| SCHEMBL31473513 | 0.98 | HTR2A (0.67) | HTR2ATAAR1NR5A1SMN1; SMN2GLA | |
| SCHEMBL5688321 | 0.98 | HTR2A (0.67) | HTR2ATAAR1NR5A1SMN1; SMN2GLA | |
| SCHEMBL17402428 | 0.98 | HTR2A (0.67) | HTR2ATAAR1NR5A1SMN1; SMN2GLA | |
| SCHEMBL1047171 | 0.96 | HTR2A (0.62) | HTR2ATAAR1SMN1; SMN2GLAMEN1 | |
| SCHEMBL3057820 | 0.89 | LMNA (0.59) | HTR2ATAAR1LMNA | |
| SCHEMBL14599625 | 0.88 | TAAR1 (0.57) | HTR2ATAAR1 | |
| SCHEMBL2163896 | 0.88 | TAAR1 (0.57) | HTR2ATAAR1 | |
| SCHEMBL11667261 | 0.88 | NR5A1 (0.62) | NR5A1SMN1; SMN2MEN1USP2ALDH1A1 | |
| SCHEMBL9036035 | 0.88 | HTR2A (0.62) | HTR2ANR5A1SMN1; SMN2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |