Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 11/20 | 0.41 |
| ▸ | NOS2 | P35228 | 11/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13370186 | 0.80 | — | — | |
| SCHEMBL19523661 | 0.77 | DAO (0.36) | — | |
| SCHEMBL11184768 | 0.76 | ESR2 (0.51) | NOS1NOS2CYP1A2LMNAMAPK1 | |
| SCHEMBL11647536 | 0.75 | CYP1A2 (0.38) | NOS1NOS2CYP1A2LMNAMAPK1 | |
| SCHEMBL11184632 | 0.75 | ESR2 (0.50) | NOS1NOS2CYP1A2LMNAMAPK1 | |
| SCHEMBL13959194 | 0.75 | CYP1A2 (0.38) | NOS1NOS2CYP1A2LMNAMAPK1 | |
| SCHEMBL21241999 | 0.74 | — | — | |
| SCHEMBL15077808 | 0.74 | — | — | |
| SCHEMBL11193083 | 0.74 | ESR2 (0.49) | NOS1NOS2CYP1A2TLR4 | |
| SCHEMBL12654511 | 0.74 | TRPA1 (0.45) | NOS1NOS2CYP1A2TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |