Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 6/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909482 | 1.00 | HSD17B3 (0.56) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8215763 | 0.85 | HSD17B3 (0.54) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8215757 | 0.85 | HSD17B3 (0.54) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6003631 | 0.77 | KDM4E (0.53) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6003635 | 0.77 | KDM4E (0.53) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6003482 | 0.74 | MAPT (0.89) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10053864 | 0.72 | APP (0.88) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6226940 | 0.72 | APP (0.88) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8215759 | 0.72 | KDM4E (0.51) | HSD17B3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11144811 | 0.72 | HSD17B3 (0.75) | HSD17B3KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312914-B1 | INDUCING MUTATATION OR CYTOTOXICITY IN A CELL; EXPOSE CELLS TO PROBES, LLUMINATE PROBE-CELL COMPLEX, DETECT LYSIS OR MUTATION IN CELLS | ORASURE TECHNOLOGIES, INC. | 2001-11-06 | — | — | US | disclosed |