Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215763 | 1.00 | HSD17B3 (0.54) | HSD17B3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL7909486 | 0.85 | HSD17B3 (0.56) | HSD17B3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL7909482 | 0.85 | HSD17B3 (0.56) | HSD17B3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL1404410 | 0.79 | GLA (0.52) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13193947 | 0.73 | APP (0.65) | HSD17B3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL3732489 | 0.73 | HSD17B3 (0.75) | HSD17B3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2029091 | 0.73 | HSD17B3 (0.75) | HSD17B3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6003482 | 0.72 | MAPT (0.89) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28543075 | 0.72 | HSD17B3 (0.62) | HSD17B3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL10053864 | 0.71 | APP (0.88) | HSD17B3KDM4EMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159686-A | Up-converting reporters for biological and other assays | SRI INTERNATIONAL (US) | 2000-12-12 | — | — | US | disclosed |