SCHEMBL7909676

SCHEMBL7909676

C=CC1CCC(CCCC[C@H]2CC[C@H](CC)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7909682 1.00 CYP1A2 (0.35) CYP1A2LMNAMAPK1HTTSIGMAR1
SCHEMBL7901962 0.94 CYP1A2 (0.32) CYP1A2
SCHEMBL7901953 0.94 CYP1A2 (0.32) CYP1A2
SCHEMBL7901965 0.94 CYP1A2 (0.32) CYP1A2
SCHEMBL9418436 0.89 ALDH1A1 (0.32)
SCHEMBL7902041 0.88 CYP1A2 (0.40) CYP1A2LMNAMAPK1HTTSIGMAR1
SCHEMBL7902059 0.88 CYP1A2 (0.50) CYP1A2LMNAMAPK1HTT
SCHEMBL7901817 0.88 CYP1A2 (0.45) CYP1A2LMNAMAPK1HTT
SCHEMBL2385898 0.88 CYP1A2 (0.45) CYP1A2LMNAMAPK1HTT
SCHEMBL7902057 0.88 CYP1A2 (0.50) CYP1A2LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750028-B1 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2001-04-18 EP disclosed
US-5776367-A Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-07-07 US disclosed
EP-0750028-A2 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-12-27 EP disclosed