Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909533 | 0.79 | CHRM1 (0.31) | — | |
| SCHEMBL14875445 | 0.79 | CHRM1 (0.45) | BUB1 | |
| SCHEMBL11895176 | 0.69 | CHRM1 (0.62) | — | |
| SCHEMBL3805945 | 0.68 | CHRM1 (0.47) | BUB1 | |
| SCHEMBL7900360 | 0.63 | CHRM1 (0.51) | BUB1 | |
| SCHEMBL5539875 | 0.63 | GRM5 (0.40) | — | |
| SCHEMBL11895473 | 0.60 | CHRM1 (0.64) | — | |
| SCHEMBL11895446 | 0.59 | CHRM1 (0.70) | — | |
| SCHEMBL11895298 | 0.58 | CHRM1 (0.53) | — | |
| SCHEMBL11955187 | 0.58 | CHRM1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096338-A1 | PYRAZOLO [4,3-c] CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-26 | — | — | WO | disclosed |