Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909724 | 0.79 | BUB1 (0.32) | — | |
| SCHEMBL14875330 | 0.78 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL15107493 | 0.67 | CHRM1 (0.38) | CHRM1 | |
| SCHEMBL7907824 | 0.65 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL7901657 | 0.65 | BUB1 (0.33) | CHRM1 | |
| SCHEMBL7900360 | 0.64 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL3805510 | 0.63 | GRN (0.43) | CHRM1 | |
| SCHEMBL11895178 | 0.60 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL3805945 | 0.59 | CHRM1 (0.47) | CHRM1 | |
| SCHEMBL6913110 | 0.58 | CHRM1 (0.43) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096338-A1 | PYRAZOLO [4,3-c] CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-26 | — | — | WO | disclosed |