SCHEMBL790990

SCHEMBL790990

c1ccc(C2(c3ccccc3)CC3CCC2C3)cc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 18/20 0.67
ALOX5 P09917 1/20 0.44
HSD11B1 P28845 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26145359 0.85 ALOX5AP (0.52) ALOX5APALOX5HSD11B1
SCHEMBL3588147 0.81 ALOX5AP (1.00) ALOX5APALOX5
SCHEMBL807663 0.81 ALOX5AP (0.55) ALOX5APHSD11B1
SCHEMBL9182059 0.81 ALOX5AP (0.55) ALOX5APALOX5HSD11B1
SCHEMBL12954721 0.81 ALOX5AP (0.63) ALOX5APALOX5HSD11B1
SCHEMBL259032 0.81 ALOX5AP (0.63) ALOX5APALOX5HSD11B1
SCHEMBL1458848 0.78 ALOX5AP (0.46) ALOX5AP
SCHEMBL3582800 0.77 ALOX5AP (0.51) ALOX5APALOX5HSD11B1
SCHEMBL11028108 0.77 ALOX5AP (0.48) ALOX5AP
SCHEMBL10112732 0.77 ALOX5AP (0.62) ALOX5APALOX5HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616493-B1 POLYMERISATION METHOD UNIV COURT UNIV OF EDINBURGH (GB) 2020-07-01 EP disclosed
US-9018270-B2 Method for producing polymers comprising multiple repeat units of bicyclic diamines UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2015-04-28 US disclosed
US-20130267616-A1 Polymerisation Method UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-10 US disclosed
EP-2616493-A1 POLYMERISATION METHOD University College Cardiff Consultants, Ltd. (GB) 2013-07-24 EP disclosed
WO-2012035327-A1 POLYMERISATION METHOD UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-22 WO disclosed
EP-2336245-A1 Polycarbonate compounds with improved surface hardness Bayer MaterialScience AG (DE) 2011-06-22 EP disclosed
EP-2333011-A1 Polycarbonate compounds with improved surface hardness Bayer MaterialScience AG (DE) 2011-06-15 EP disclosed
US-7341811-B2 Electrophotographic photoreceptor using the electron transferring compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-03-11 US disclosed
US-20050118519-A1 Electron transferring compound and electrophotographic photoreceptor using the electron transferring compound S-PRINTING SOLUTION CO., LTD. (KR) 2005-06-02 US disclosed
US-5629418-A PRECIPITATION OF AMORPHOUS MATERIAL WITH ACID, KEEPING AMORPHOUS MATERIAL CONTINUOUSLY WET, CRYSTALLIZATION WITH ORGANIC SOLVENT EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0709437-A2 Method for preparing titanyl fluorophthalocyanines, electrophotographic elements, and titanyl fluorophthalocyanine compositions EASTMAN KODAK COMPANY (US) 1996-05-01 EP disclosed