Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87608 | 0.82 | HSD11B1 (0.55) | ALOX5APPTGS2HSD11B1ATMHTT | |
| SCHEMBL11893304 | 0.82 | KMT2A (0.47) | ALOX5APHSD11B1MEN1KMT2A | |
| SCHEMBL979119 | 0.82 | ALOX5AP (0.39) | ALOX5APPTGS2HSD11B1KMT2A | |
| SCHEMBL18905268 | 0.82 | ALOX5AP (0.39) | ALOX5APPTGS2HSD11B1KMT2A | |
| SCHEMBL18905267 | 0.80 | ALOX5AP (0.42) | ALOX5APPTGS2HSD11B1ALOX5MEN1 | |
| SCHEMBL12948046 | 0.78 | HSD11B1 (0.39) | ALOX5APHSD11B1 | |
| SCHEMBL87607 | 0.77 | ALOX5AP (0.38) | ALOX5APHSD11B1 | |
| SCHEMBL13548738 | 0.77 | ALOX5AP (0.38) | ALOX5APHSD11B1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL790990 | 0.77 | ALOX5AP (0.67) | ALOX5APHSD11B1ALOX5 | |
| SCHEMBL18905475 | 0.76 | ALOX5AP (0.38) | ALOX5APPTGS2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230152693-A1 | CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20100152185-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | CHU LIN | 2010-06-17 | — | — | US | disclosed |
| US-7629467-B2 | 5-lipoxygenase activating protein inhibitors; antiatherosclerotic, antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK & CO., INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20060211677-A1 | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211677-A1 | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use | ALOX5, ALOX15B, ALOX15 | ALOX5AP 10/4885PTGS2 22/4885HSD11B1 520/4885 |
| US-20100152185-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | ALOX5, LTC4S, ALOX15 | ALOX5AP 16/4885PTGS2 19/4885HSD11B1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.