Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910103 | 1.00 | ESR2 (0.37) | ESR2CYP2C9ESR1CYP3A4ALDH1A1 | |
| SCHEMBL7912333 | 0.86 | CYP3A4 (0.36) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL7912331 | 0.86 | CYP3A4 (0.36) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL7912562 | 0.85 | ESR2 (0.38) | ESR2CYP2C9ESR1CYP3A4 | |
| SCHEMBL7912569 | 0.85 | ESR2 (0.38) | ESR2CYP2C9ESR1CYP3A4 | |
| SCHEMBL7909912 | 0.83 | SPHK1 (0.34) | ESR2 | |
| SCHEMBL7909919 | 0.83 | SPHK1 (0.34) | ESR2 | |
| SCHEMBL7912768 | 0.82 | ESR2 (0.34) | ESR2CYP2C9ESR1CYP3A4 | |
| SCHEMBL7912763 | 0.82 | ESR2 (0.34) | ESR2CYP2C9ESR1CYP3A4 | |
| SCHEMBL7916040 | 0.82 | SPHK1 (0.44) | ESR2CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0857708-A1 | LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-08-12 | — | — | EP | disclosed |