Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 8/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600267 | 0.89 | KCNE1 (0.48) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL7900354 | 0.87 | KCNE1 (0.46) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL6603010 | 0.87 | CNR2 (0.43) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL7479185 | 0.87 | KCNE1 (0.53) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL6601715 | 0.86 | KCNE1 (0.42) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL6600820 | 0.86 | KCNE1 (0.47) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL7913683 | 0.84 | KCNE1 (0.36) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL6602717 | 0.84 | KCNE1 (0.43) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL8482616 | 0.83 | KCNE1 (0.49) | KCNE1KCNQ1KCNH2MEN1KMT2A | |
| SCHEMBL8476685 | 0.82 | KCNE1 (0.53) | KCNE1KCNQ1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |