Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | LDLR | P01130 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904188 | 0.92 | LDLR (0.36) | FNTAFNTBLDLR | |
| SCHEMBL7910446 | 0.85 | FNTA (0.38) | BRS3FNTAFNTB | |
| SCHEMBL7910168 | 0.84 | FNTA (0.56) | FNTAFNTB | |
| Lithium SCHEMBL7910170 | 0.84 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL7907084 | 0.84 | FNTA (0.35) | BRS3FNTAFNTBLDLRCYSLTR2 | |
| SCHEMBL7905934 | 0.83 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL7910292 | 0.79 | BRS3 (0.41) | BRS3FNTAFNTB | |
| SCHEMBL7905228 | 0.77 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL7897786 | 0.76 | PDE4D (0.36) | FNTAFNTBLDLR | |
| SCHEMBL7918444 | 0.74 | FNTA (0.40) | BRS3FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |