Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905228 | 0.92 | FNTA (0.37) | FNTAFNTBRENMAPK11 | |
| SCHEMBL7910304 | 0.85 | BRS3 (0.38) | FNTAFNTBBRS3 | |
| SCHEMBL7905223 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7905226 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| Lithium SCHEMBL7910397 | 0.84 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL7910393 | 0.84 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL7910577 | 0.82 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7907084 | 0.82 | FNTA (0.35) | FNTAFNTBBRS3MAPK11 | |
| SCHEMBL7910437 | 0.80 | FNTA (0.42) | FNTAFNTBBRS3ADRB3ADRB1 | |
| SCHEMBL7904188 | 0.77 | LDLR (0.36) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |