⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910372 | 1.00 | — | — | |
| Biphenyl SCHEMBL27953789 | 0.84 | POLB (0.51) | — | |
| SCHEMBL17666902 | 0.82 | — | — | |
| SCHEMBL17666901 | 0.82 | — | — | |
| SCHEMBL17666971 | 0.79 | MAOA (0.45) | — | |
| SCHEMBL17666970 | 0.79 | MAOA (0.45) | — | |
| SCHEMBL3949923 | 0.76 | — | — | |
| SCHEMBL437433 | 0.76 | — | — | |
| SCHEMBL13712171 | 0.76 | — | — | |
| SCHEMBL11672130 | 0.76 | MAOA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006496-B1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORP (JP) | 2017-07-19 | — | — | EP | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| US-10919869-B2 | Thiazole derivative and applications | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-02-16 | — | — | US | disclosed |
| US-20190292162-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| EP-3459937-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | East China University of Science and Technology (CN) | 2019-03-27 | — | — | EP | disclosed |
| CN-107189487-B | Mono-azo thiazole triazole disperse dye and preparation method thereof | 南京工业大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-107189487-A | Mono-azo thiazole triazole disperse dye and preparation method thereof | 南京工业大学 | 2017-09-22 | — | — | CN | disclosed |
| EP-3006496-B1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-20160115296-A1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORPORATION (JP) | 2016-04-28 | — | — | US | disclosed |
| EP-3006496-A1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | Bridgestone Corporation (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |