Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516189 | 1.00 | KDM1A (0.41) | KDM1AEGLN2SLC22A12NR3C2CYP11B1 | |
| SCHEMBL5886343 | 0.92 | CYP2C9 (0.41) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL8676866 | 0.92 | CYP2C9 (0.41) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL8046380 | 0.90 | EGLN2 (0.39) | KDM1AEGLN2SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL8678572 | 0.90 | KDM1A (0.39) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL7507643 | 0.90 | KDM1A (0.39) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL7514456 | 0.89 | RARB (0.39) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL8677220 | 0.89 | RARB (0.39) | KDM1AEGLN2SLC22A12 | |
| SCHEMBL8047124 | 0.89 | EGLN2 (0.38) | KDM1AEGLN2 | |
| SCHEMBL8048358 | 0.88 | RARB (0.44) | KDM1AEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |