SCHEMBL8047124

SCHEMBL8047124

CCCOC[C@H]1CC[C@H](c2ccc(C(=O)O)c(-c3ccc(C#N)c(F)c3)c2)CC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 2/20 0.38
RARA P10276 1/20 0.38
RARB P10826 1/20 0.38
KDM1A O60341 12/20 0.38
MCL1 Q07820 1/20 0.35
XDH P47989 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048358 0.95 RARB (0.44) EGLN2RARARARBKDM1AMCL1
SCHEMBL8045318 0.95 RARB (0.41) EGLN2RARARARBKDM1AMCL1
SCHEMBL8046380 0.93 EGLN2 (0.39) EGLN2KDM1AXDH
SCHEMBL5886343 0.89 CYP2C9 (0.41) EGLN2KDM1A
SCHEMBL8676866 0.89 CYP2C9 (0.41) EGLN2KDM1A
SCHEMBL7516189 0.89 KDM1A (0.41) EGLN2KDM1A
SCHEMBL7910488 0.89 KDM1A (0.41) EGLN2KDM1A
SCHEMBL8678572 0.87 KDM1A (0.39) EGLN2RARARARBKDM1AMCL1
SCHEMBL7507643 0.87 KDM1A (0.39) EGLN2RARARARBKDM1AMCL1
SCHEMBL7514456 0.86 RARB (0.39) EGLN2RARARARBKDM1AMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700982-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-04-26 EP disclosed
EP-0700982-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-03-13 EP disclosed