Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910505 | 1.00 | HPGD (0.42) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL7910502 | 1.00 | HPGD (0.42) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL7907302 | 0.96 | HPGD (0.44) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL7907306 | 0.96 | HPGD (0.44) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL12032165 | 0.94 | HPGD (0.40) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL12032390 | 0.94 | HPGD (0.40) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL9405805 | 0.93 | HPGD (0.36) | HPGDGAAPOLBCYP2C9LMNA | |
| SCHEMBL7908240 | 0.93 | HPGD (0.41) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL22277291 | 0.93 | HPGD (0.41) | HPGDGAASMN1; SMN2GLAPOLB | |
| SCHEMBL7908243 | 0.93 | HPGD (0.41) | HPGDGAASMN1; SMN2GLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5178790-A | With excellent steepness of characteristics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-12 | — | — | US | disclosed |