SCHEMBL7910586

SCHEMBL7910586

CCCCC[C@H]1CC[C@H](c2ccc(OC)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.54
CYP2C9 P11712 1/20 0.46
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
SPHK1 Q9NYA1 3/20 0.43
ESR2 Q92731 1/20 0.41
GRM2 Q14416 1/20 0.41
RAB9A P51151 1/20 0.40
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910589 1.00 DRD2 (0.54) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL21321988 0.98 DRD2 (0.52) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL19722191 0.98 DRD2 (0.52) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL19722184 0.98 DRD2 (0.52) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL10766094 0.96 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL223652 0.96 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL10766092 0.96 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL222090 0.96 DRD2 (0.50) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL8368583 0.95 DRD2 (0.55) DRD2CYP2C9MAPTALDH1A1MEN1
SCHEMBL8368584 0.95 DRD2 (0.55) DRD2CYP2C9MAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57183730-A None JP disclosed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5951913-A Liquid crystal compositions comprising silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-09-14 US disclosed
EP-0394417-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-08-04 EP disclosed
EP-0438547-B2 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-07-07 EP disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
EP-0494368-B1 Supertwist liquid crystal display MERCK PATENT GMBH (DE) 1999-01-20 EP disclosed
EP-0481293-B1 Supertwist liquid crystal display MERCK PATENT GMBH (DE) 1996-06-05 EP disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0366985-B1 Super twist liquid crystal display MERCK PATENT GMBH (DE) 1994-04-06 EP disclosed
EP-0365641-A1 PYRIDINE DERIVATIVES MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed
WO-1989010356-A1 PYRIDINE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-11-02 WO disclosed
US-4877547-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-31 US disclosed
EP-0302916-A1 ELECTRO-OPTICAL DISPLAY ELEMENT. MERCK PATENT GMBH (DE) 1989-02-15 EP disclosed
WO-1988006178-A1 ELECTRO-OPTICAL DISPLAY ELEMENT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-08-25 WO disclosed
EP-0258346-A1 LIQUID CRYSTAL DISPLAY ELEMENT. MERCK PATENT GMBH (DE) 1988-03-09 EP disclosed
EP-0258349-A1 ELECTRO-OPTICAL DISPLAY ELEMENT. MERCK PATENT GMBH (DE) 1988-03-09 EP disclosed
WO-1987005318-A1 ELECTRO-OPTICAL DISPLAY ELEMENT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1987-09-11 WO disclosed
WO-1987005317-A1 LIQUID CRYSTAL DISPLAY ELEMENT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1987-09-11 WO disclosed
JP-S57183730-A LIQUID CRYSTAL COMPOUND SEIKO EPSON CORP 1982-11-12 JP disclosed