Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183815 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183672 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183675 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183741 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183811 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183828 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183654 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183633 | 0.94 | TACR3 (0.50) | TACR3POLBCNR2NAAAALDH1A1 | |
| SCHEMBL17183807 | 0.91 | TACR3 (0.46) | TACR3POLBGPR88ALDH1A1NPSR1 | |
| SCHEMBL10483621 | 0.84 | ALDH1A1 (0.55) | TACR3POLBALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |