SCHEMBL7910889

SCHEMBL7910889

CCCc1ccc(-c2ccc(CCC3CCC(C4CCC(CCCCF)CC4)CC3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
MAOA P21397 1/20 0.43
GPR84 Q9NQS5 1/20 0.36
NISCH Q9Y2I1 1/20 0.33
KCNH2 Q12809 2/20 0.32
HRH3 Q9Y5N1 3/20 0.32
MCL1 Q07820 1/20 0.31
RARB P10826 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7910886 1.00 MAOB (0.43) MAOBMAOAGPR84NISCHKCNH2
SCHEMBL7910892 1.00 MAOB (0.43) MAOBMAOAGPR84NISCHKCNH2
SCHEMBL7909883 0.96 MAOB (0.46) MAOBMAOAGPR84NISCHKCNH2
SCHEMBL7912976 0.94 MAOB (0.45) MAOBMAOAGPR84KCNH2HRH3
SCHEMBL7912978 0.94 MAOB (0.45) MAOBMAOAGPR84KCNH2HRH3
SCHEMBL7912982 0.94 MAOB (0.45) MAOBMAOAGPR84KCNH2HRH3
SCHEMBL7912972 0.94 MAOB (0.45) MAOBMAOAGPR84KCNH2HRH3
SCHEMBL7911047 0.93 RARB (0.39) MAOBMAOAGPR84NISCHHRH3
SCHEMBL7911054 0.93 RARB (0.39) MAOBMAOAGPR84NISCHHRH3
SCHEMBL7911059 0.93 RARB (0.39) MAOBMAOAGPR84NISCHHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174456-B1 STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE CHISSO CORPORATION (JP) 2001-01-16 US disclosed
EP-0857708-A1 LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-08-12 EP disclosed