SCHEMBL7912982

SCHEMBL7912982

CCCc1ccc(CC[C@H]2CC[C@H]([C@H]3CC[C@H]([C@H]4CC[C@H](CCCCCF)CC4)CC3)CC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.45
MAOA P21397 1/20 0.45
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
S1PR3 Q99500 1/20 0.33
HTR2A P28223 1/20 0.33
KCNH2 Q12809 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
SPHK1 Q9NYA1 3/20 0.33
HRH3 Q9Y5N1 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
NMT1 P30419 1/20 0.32
SPHK2 Q9NRA0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912978 1.00 MAOB (0.45) MAOBMAOACYP3A4CYP2C8CYP2D6
SCHEMBL7912972 1.00 MAOB (0.45) MAOBMAOACYP3A4CYP2C8CYP2D6
SCHEMBL7912976 1.00 MAOB (0.45) MAOBMAOACYP3A4CYP2C8CYP2D6
SCHEMBL7910886 0.94 MAOB (0.43) MAOBMAOAKCNH2HRH3GPR84
SCHEMBL7910892 0.94 MAOB (0.43) MAOBMAOAKCNH2HRH3GPR84
SCHEMBL7910889 0.94 MAOB (0.43) MAOBMAOAKCNH2HRH3GPR84
SCHEMBL7902578 0.91 MAOA (0.39) MAOBMAOAHTR2AITGB3ITGA2B
SCHEMBL7902570 0.91 MAOA (0.39) MAOBMAOAHTR2AITGB3ITGA2B
SCHEMBL7902567 0.91 MAOA (0.39) MAOBMAOAHTR2AITGB3ITGA2B
SCHEMBL7902574 0.91 MAOA (0.39) MAOBMAOAHTR2AITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174456-B1 STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE CHISSO CORPORATION (JP) 2001-01-16 US disclosed
EP-0857708-A1 LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-08-12 EP disclosed