SCHEMBL7911025

SCHEMBL7911025

CCC1CCC(c2ccc(-c3ccc(OC(F)(F)C(F)C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 2/20 0.34
CYP2C9 P11712 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDO1 P14902 1/20 0.33
KDM1A O60341 2/20 0.32
LMNA P02545 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
MAPK1 P28482 1/20 0.32
ESR2 Q92731 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
DGAT1 O75907 2/20 0.32
SOAT1 P35610 1/20 0.32
DRD2 P14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914023 0.96 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7913245 0.91 CYP2C9 (0.43) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7903220 0.90 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10CYP2C9IDO1
SCHEMBL7903774 0.89 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7914081 0.89 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7913714 0.89 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7913713 0.89 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7911877 0.88 CYP2C9 (0.41) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7917348 0.88 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL7911198 0.88 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed