SCHEMBL7911210

SCHEMBL7911210

CCCC1CCC(COc2ccc(OC(F)(F)C(F)C(F)(F)F)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PARP15 Q460N3 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
ABHD6 Q9BV23 1/20 0.37
ACACB O00763 1/20 0.35
PDK2 Q15119 1/20 0.35
CETP P11597 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911171 0.96 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10PARP15PARP10
SCHEMBL7903600 0.84 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10CETP
SCHEMBL7917364 0.84 CYP2C9 (0.46) ALDH1A1TSHRHSD17B10ACACB
SCHEMBL8834213 0.82 SCN9A (0.37) PARP15PARP10ABHD6ACACBPDK2
SCHEMBL7903591 0.82 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10ACACB
SCHEMBL7914087 0.81 CYP2C9 (0.43) ALDH1A1TSHRHSD17B10ACACB
SCHEMBL7913245 0.81 CYP2C9 (0.43) ALDH1A1TSHRHSD17B10
SCHEMBL7912009 0.81 CYP2C9 (0.43) ALDH1A1TSHRHSD17B10ACACB
SCHEMBL7917601 0.81 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10CETP
SCHEMBL7911208 0.81 CYP2C9 (0.41) ALDH1A1TSHRHSD17B10ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed