SCHEMBL7911214

SCHEMBL7911214

CCCCCC1CCC(C2CCC(CCc3ccc(-c4ccc(OC(F)(F)C(F)C(F)(F)F)cc4)cc3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
CETP P11597 1/20 0.32
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31
MAOB P27338 2/20 0.31
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31
GAA P10253 1/20 0.31
EPHX2 P34913 1/20 0.31
MAOA P21397 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911229 0.97 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10CETPITGB3
SCHEMBL7917350 0.97 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10MAPTKDM4E
SCHEMBL7914130 0.96 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10MAPTKDM4E
SCHEMBL7911901 0.93 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MAPTKDM4E
SCHEMBL7903777 0.93 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MAPTKDM4E
SCHEMBL7911916 0.93 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10CETPITGB3
SCHEMBL9472034 0.89 CETP (0.37) CETPITGB3ITGA2BMAOBPPARG
SCHEMBL7917601 0.89 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPTKDM4E
SCHEMBL9340776 0.89 CETP (0.37) CETPITGB3ITGA2BMAOBPPARG
SCHEMBL9336620 0.88 CETP (0.36) MAPTCETPITGB3ITGA2BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed