Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725739 | 0.88 | KMT2A (0.53) | USP2KDM4ECYP2C9ALDH1A1MAPT | |
| SCHEMBL23051536 | 0.88 | USP2 (0.69) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL1663774 | 0.86 | USP2 (0.62) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL1663654 | 0.83 | USP2 (0.66) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL380124 | 0.82 | USP2 (0.57) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL23051641 | 0.82 | USP2 (0.69) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL27629259 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2952106 | 0.79 | USP2 (0.54) | USP2KDM4EHRH1CCR3KCNH2 | |
| SCHEMBL156068 | 0.79 | ADRB1 (0.47) | MAPTGPR119 | |
| SCHEMBL7914429 | 0.79 | SLC6A2 (0.48) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072593-A1 | LIQUID CRYSTALLINE COMPOUND HAVING PIPERIDINE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2001-01-31 | — | — | EP | disclosed |