Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926277 | 0.86 | ALDH1A1 (0.51) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL7907633 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL5209075 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL926707 | 0.82 | IDO1 (0.46) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL1865811 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GAAGFERMAPTCYP4F2 | |
| SCHEMBL5531563 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL5522622 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAGFERMAPTMAPK1 | |
| SCHEMBL7898745 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAGFERMAPTCYP4F2 | |
| SCHEMBL3235701 | 0.77 | PPARD (0.45) | ALDH1A1GAAGFERMAPTCYP4F2 | |
| SCHEMBL14592239 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAGFERMAPTCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |