Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | PPARA | Q07869 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590532 | 0.90 | KDM4E (0.70) | FFAR1PPARGPPARAMAPTKDM4E | |
| SCHEMBL4034286 | 0.89 | FFAR1 (0.69) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL6156630 | 0.87 | FFAR1 (0.71) | FFAR1PPARGPPARAMAPTKDM4E | |
| SCHEMBL4893515 | 0.86 | KDM4E (0.70) | FFAR1PPARGPPARAMAPTKDM4E | |
| SCHEMBL2930640 | 0.86 | KDM4E (0.74) | FFAR1PPARGPPARAMAPTKDM4E | |
| SCHEMBL6607518 | 0.83 | LMNA (0.60) | MAPTKDM4ETP53SMN1; SMN2POLB | |
| SCHEMBL5105247 | 0.83 | PPARG (0.70) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL4032172 | 0.83 | FFAR1 (0.58) | FFAR1PPARGPPARAMAPTTP53 | |
| SCHEMBL3531377 | 0.82 | KDM4E (0.61) | FFAR1PPARGPPARAMAPTKDM4E | |
| SCHEMBL4032011 | 0.82 | FFAR1 (0.70) | FFAR1PPARGPPARAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |