Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169364 | 0.91 | — | — | |
| SCHEMBL2134849 | 0.81 | — | — | |
| SCHEMBL14646646 | 0.81 | TSHR (0.54) | TSHRMAPTALDH1A1LMNADNM1 | |
| SCHEMBL5573755 | 0.80 | MAPT (0.42) | TSHRMAPTCES2LMNADNM1 | |
| SCHEMBL11518919 | 0.78 | MAPT (0.41) | TSHRMAPTCES2LMNADNM1 | |
| SCHEMBL14646606 | 0.78 | MAPT (0.41) | TSHRMAPTCES2ALDH1A1LMNA | |
| SCHEMBL24926247 | 0.78 | MAPT (0.52) | TSHRMAPTCES2LMNADNM1 | |
| SCHEMBL18725210 | 0.78 | MAPT (0.52) | TSHRMAPTCES2LMNADNM1 | |
| SCHEMBL19026469 | 0.78 | MAPT (0.52) | TSHRMAPTCES2LMNADNM1 | |
| SCHEMBL10608053 | 0.78 | MAPT (0.52) | TSHRMAPTCES2LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338175-C | Chiral liquid crystal compounds having fluorine-containing terminal moieties | MINNESOTA MINING & MFG (US) | 2007-09-19 | — | — | CN | disclosed |
| CN-1326494-A | Chiral liquid crystal compounds having fluorinated terminal portion | MINNESOTA MINING & MFG (US) | 2001-12-12 | — | — | CN | disclosed |
| EP-1135450-A1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6139924-A | CONTAINING A PYRIMIDINE RING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000031210-A1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |