Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904582 | 0.90 | PDE4D (0.41) | PDE4DPDE4BSNCAGUSB | |
| SCHEMBL4326850 | 0.89 | TAAR1 (0.47) | PDE4DPDE4BMAPTSNCA | |
| SCHEMBL3467080 | 0.88 | PDE4B (0.42) | PDE4DPDE4BMEN1MAPTKMT2A | |
| SCHEMBL3791461 | 0.88 | PDE4D (0.44) | PDE4DPDE4BMAPTCYP19A1SNCA | |
| SCHEMBL8057832 | 0.88 | PDE4D (0.49) | PDE4DPDE4BMEN1MAPTKMT2A | |
| SCHEMBL4326854 | 0.87 | PDE4D (0.48) | PDE4DPDE4BMEN1MAPTKMT2A | |
| SCHEMBL15906153 | 0.87 | PDE4B (0.38) | PDE4DPDE4BMAPTGUSB | |
| SCHEMBL4326556 | 0.86 | PDE4B (0.41) | PDE4DPDE4BMAPTSNCA | |
| SCHEMBL3789377 | 0.86 | PDE4D (0.39) | PDE4DPDE4B | |
| SCHEMBL7902765 | 0.86 | PDE4B (0.39) | PDE4DPDE4BFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |