Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918457 | 0.90 | MEN1 (0.60) | SHMT2MAPTKDRMEN1KMT2A | |
| SCHEMBL7904898 | 0.87 | MAPT (0.59) | SHMT2MAPTKDRMEN1KMT2A | |
| SCHEMBL7912018 | 0.85 | KDR (0.74) | MAPTKDRMEN1KMT2ARXFP1 | |
| SCHEMBL7904894 | 0.85 | MAPT (0.62) | MAPTKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL7904825 | 0.84 | MAPT (0.63) | MAPTKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL7918610 | 0.82 | MEN1 (0.56) | MAPTKDRMEN1KMT2ARXFP1 | |
| SCHEMBL7915149 | 0.81 | MAPT (0.52) | MAPTKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL7905044 | 0.81 | MAPT (0.55) | MAPTKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL7913390 | 0.81 | MAPT (0.56) | MAPTKDRMEN1KMT2ARXFP1 | |
| SCHEMBL7912171 | 0.81 | KDR (0.62) | MAPTKDRMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |