Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15783190 | 0.91 | KDR (0.70) | KDRMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL7915100 | 0.90 | KDR (0.72) | KDRMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL7905062 | 0.90 | RXFP1 (0.71) | KDRMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL15783186 | 0.86 | KDR (0.81) | KDRMEN1KMT2AMAPTLMNA | |
| SCHEMBL7911801 | 0.85 | SHMT2 (0.59) | KDRMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL3028329 | 0.85 | KDR (1.00) | KDRMEN1KMT2AMAPTLMNA | |
| SCHEMBL14235459 | 0.84 | KDR (0.78) | KDRMEN1KMT2AMAPTLMNA | |
| SCHEMBL7918597 | 0.82 | RXFP1 (0.57) | KDRMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL15077148 | 0.82 | KDR (0.81) | KDRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15783189 | 0.82 | KDR (0.75) | KDRMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |