Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901849 | 1.00 | TERT (0.42) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL31672982 | 0.90 | PPARG (0.52) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL8861361 | 0.90 | PPARG (0.52) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL8861363 | 0.90 | PPARG (0.52) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL1705893 | 0.88 | F7 (0.48) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL5981223 | 0.88 | F7 (0.48) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL1705896 | 0.88 | F7 (0.48) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23829791 | 0.83 | HDAC2 (0.40) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23829790 | 0.83 | HDAC2 (0.40) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23922605 | 0.82 | HDAC2 (0.39) | PGRTDP1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200254-B1 | PRACTICAL SYNTHETIC ROUTES TO CYCLOALKADIENONES AND SATURATED AND MONO-UNSATURATED MACROCYCLIC KETONES WITH CLAISEN REARRANGEMENT OF BIS ALLYL ALCOHOLS, RING CYCLIZATION REACTION, AND SUBSEQUENT REDUCTION OR DECARBOALKOXYLATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-03-13 | — | — | US | disclosed |