SCHEMBL791197

SCHEMBL791197

CNc1c(O)c(=O)c1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL409685 0.77
Dimethylamine SCHEMBL28933326 0.74 GSR (0.32)
SCHEMBL21252624 0.71
SCHEMBL20050249 0.70
SCHEMBL13929572 0.70 ALDH1A1 (0.41)
SCHEMBL14327880 0.70 CXCR2 (0.41)
SCHEMBL21842697 0.67 GAA (0.40)
SCHEMBL20194036 0.67
Methyl Alcohol SCHEMBL28845780 0.66 GSR (0.35)
SCHEMBL5634965 0.65 GRIN2D (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405455-B1 2-OXINDOLE COMPOUNDS CHEMOCENTRYX INC (US) 2024-02-28 EP disclosed
WO-2023239634-A2 INHIBITORS OF BACTERIAL TYPE III SECRETION SYSTEM MICROBIOTIX, INC. (US) 2023-12-14 WO disclosed
EP-4037768-B1 NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI SA (FR) 2023-10-11 EP disclosed
US-20230270709-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION FOR TOPICAL ADMINISTRATION CHRISTIAN-ALBRECHTS-UNIVERSITAT ZU KIEL (DE) 2023-08-31 US disclosed
US-20230270709-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION FOR TOPICAL ADMINISTRATION CHRISTIAN-ALBRECHTS-UNIVERSITAT ZU KIEL (DE) 2023-08-31 US disclosed
US-11530207-B2 Compounds for the treatment of cancer SKYHAWK THERAPEUTICS, INC. (US) 2022-12-20 US disclosed
US-11447452-B2 Agonists of peroxisome proliferator-activated receptor alpha and methods of use THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2022-09-20 US disclosed
EP-3440073-B1 KINASE INHIBITORS OXULAR ACQUISITIONS LTD (GB) 2022-06-08 EP disclosed
US-11337968-B2 Phenylquinoline compositions for treatment of ocular disorders and conditions THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2022-05-24 US disclosed
EP-3253745-B1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2021-09-29 EP disclosed
US-20090036444-A1 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2009-02-05 US disclosed
US-20090036444-A1 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2009-02-05 US disclosed
US-7439258-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM (CANADA) LTD (CA) 2008-10-21 US disclosed
US-7439258-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM (CANADA) LTD (CA) 2008-10-21 US disclosed
EP-1891951-A1 Viral polymerase inhibitors BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2008-02-27 EP disclosed
WO-2008009924-A2 INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2008-01-24 WO disclosed
US-7294457-B2 Direct binding assay for identifying inhibitors of HCV polymerase BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2007-11-13 US disclosed
US-7294457-B2 Direct binding assay for identifying inhibitors of HCV polymerase BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2007-11-13 US disclosed
US-20070049593-A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2007-03-01 US disclosed
US-20070049593-A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2007-03-01 US disclosed