Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904969 | 0.94 | HTT (0.58) | MAPTTP53NPSR1HTTALDH1A1 | |
| SCHEMBL7913357 | 0.84 | NPSR1 (0.56) | MAPTTP53NPSR1HTTALDH1A1 | |
| SCHEMBL7915135 | 0.82 | NPSR1 (0.65) | MAPTTP53NPSR1HTTALDH1A1 | |
| SCHEMBL7912131 | 0.80 | NPSR1 (0.65) | MAPTTP53NPSR1HTTALDH1A1 | |
| SCHEMBL7913387 | 0.79 | NPSR1 (0.87) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL7914915 | 0.77 | HTT (0.61) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL7914758 | 0.77 | NPSR1 (0.61) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL7913320 | 0.77 | NPSR1 (0.61) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL7904890 | 0.77 | NPSR1 (0.61) | MAPTNPSR1HTTALDH1A1LMNA | |
| SCHEMBL7918635 | 0.77 | HTT (0.72) | MAPTTP53NPSR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |