Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965124 | 0.85 | KMT2A (0.79) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7914973 | 0.84 | NPSR1 (0.73) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7915135 | 0.83 | NPSR1 (0.65) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7913320 | 0.83 | NPSR1 (0.61) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7904890 | 0.83 | NPSR1 (0.61) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7913387 | 0.83 | NPSR1 (0.87) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7914758 | 0.83 | NPSR1 (0.61) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7904969 | 0.78 | HTT (0.58) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7912079 | 0.77 | MAPT (0.60) | HTTNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL7913357 | 0.76 | NPSR1 (0.56) | HTTNPSR1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |