⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284651 | 0.74 | — | — | |
| SCHEMBL23890300 | 0.72 | — | — | |
| SCHEMBL10211672 | 0.70 | — | — | |
| SCHEMBL14191850 | 0.69 | — | — | |
| SCHEMBL11997023 | 0.67 | — | — | |
| SCHEMBL10005358 | 0.67 | — | — | |
| SCHEMBL272823 | 0.65 | — | — | |
| SCHEMBL16372970 | 0.65 | — | — | |
| Bromide SCHEMBL9736200 | 0.64 | — | — | |
| SCHEMBL18285616 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021233394-A1 | RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS INCLUDING PIPERAZINE HETEROCYCLIC AMIDE UREAS | Sironax Ltd. (KY) | 2021-11-25 | — | — | WO | disclosed |
| EP-3444237-B1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| WO-2019144132-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | RADIUS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |
| US-20120130147-A1 | METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS | FINSINGER DIRK (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |